General Cell Based Assays
Eurofins Discoverx PathHunter eXpress PTGER4 HEK 293 β-Arrestin GPCR Assay, 10pl Kit. (93-0304E1CP0L)
The PathHunter PTGER4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin E2) based activation of PTGER4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGER4 and EA-tagged β-Arrestin-2. Activation of PTGER4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF CD16a (FcgRIIIa, F158) Cellular Binding Kit, 100 Assay Points
HTRF CD16a (FcgRIIIa, F158) Cellular Binding Kit, 100 Assay Points
Cayman Chemical Cel-Based asy Glucose OxId 2mg
An ionizable cationic lipid (pKa 6.5) has been used in the generation of LNPs for the delivery of mRNA and anticancer agents in vivo LNPs containing DMT7 and encapsulating mRNA encoding Il-12 and MSA-2 decrease tumor volume lung metastatic nodule numbers and lung levels of CD4 and CD8 T cells in a 4T1 breast cancer mouse xenograft model of lung metastasis the same LNPs decrease the number of Tregs increase the number of tumor-associated M1 macrophages and increase intratumoral levels of Il-12 Il-2 Tnf-a and Ifn-? in a B16/F10 murine melanoma model
Eurofins Discoverx HitHunter cAMP Assay for Biologics, 1,000/4,000 dp (96-well/384-well). (90-0075LM10)
This detection kit is a robust, sensitive and easy-to-use assay to determine GPCR activity through detection of intracellular cAMP levels. The HitHunter cAMP assay is intended for use with cells expressing Gαs- or GαI-coupled GPCRs. This product uses EFC technology, and contains ED-tagged cAMP, anti-cAMP antibody, and pure EA. Upon application to a cell which contains endogenous, untagged cAMP, the anti-cAMP antibody will be sequestered by binding to this untagged cAMP, allowing for EFC between the tagged cAMP and soluble EA. This will produce a proportional level of chemiluminescent signal. This kit format is intended for Biologic drugs with a protocol optimized for use in a 96-well plate. This kit may be used with Eurofins DiscoverX cAMP cell lines as well as cell lines from other sources. This detection kit contains reagents for assaying 10 plates (96-well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Eurofins Discoverx AssayComplete Cell Plating 23 Reagent, 500. (93-0563R23B)
AssayComplete Cell Plating 23 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress mCXCR6 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0512E2MCP0L)
The PathHunter mCXCR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL16) based activation of mCXCR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR6 and EA-tagged β-Arrestin-2. Activation of mCXCR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam DNMT Activity Assay Kit (Fluorometric)
DNMT Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Crystal Chem Inc Mouse Glucose Assay Kit, 96-tests
The Mouse Glucose Assay is used to quantify levels of glucose in mouse serum, plasma, and urine using only a 2 µL sample volume. Highlights: Easy-to-use, results in 5 minutes. Kits use a sample size of only 2 µL. For use with serum, plasma, and urine. Designed for mouse samples. Crystal Chem is a worldwide leading supplier of mouse and rat ELISA kits for research use. Our kits are among the highest quality found in the market, and are used by leading research universities, pharma companies, and government institutions around the world.
Abcam Senescence Detection Kit
Senescence Detection Kit
The product is subject to the following: Abcam Restricted Use Statement
Revvity Health Sciences Inc HTRF Human Total Phospholamban Detection Kit, 500 Assay Points
HTRF Human Total Phospholamban Detection Kit, 500 Assay Points
Abcam Phenylalanine Assay Kit (Colorimetric)
Phenylalanine Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Enzo Life Sciences Caspase-fluorometric substrate set (1 Set)
Fluorometric substrates for assaying activities of members of caspase family proteases. All substrates are provided in liquid ready-to-use form. Long Term Storage: -20°C. Applications: Fluorescence microscopy .
BioVendor, LLC QuickZyme Sensitive Tissue Hydroxyproline Kit 5 X 96-Assays (for collagen analysis)
QuickZyme Sensitive Tissue Hydroxyproline Kit, 5 X 96-Assays. Measure hydroxyproline in small tissue samples with low collagen levels! The ONLY hydroxyproline-based assay which shows no matrix effect and no need for further dilution of the hydrolysate, enabling measurement in small samples with low hydroxyproline levels. No drying of hydrolysate is needed, resulting in a fast (<2 hrs), sensitive and easy (96-well plate format) assay. Dynamic range: 6-300 uM. Sensitivity: 0.3 ug/ml. Species independent. Measures total hydroxyproline. If this hydroxyproline is obtained upon hydrolysis of collagen, it represents all collagen types present without discriminating between types of collagen, procollagen, mature collagen and collagen degradation products. Hydroxyproline in tissue hydrolysates can be used as a direct measure of the amount of collagen present. Collagen hydrolysis tubes & protocol not included (if these items are needed, please order QuickZyme Sensitive Tissue Collagen Assay).