General Cell Based Assays
Eurofins Discoverx PathHunter eXpress VISTA/VISTA Dimerization Assay, 10pl Kit. (93-1079E3CP5L)
The PathHunter VISTA/VISTA Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand induced dimerization of VISTA/VISTA receptors. This product uses EFC technology. The cell line included overexpresses VISTA target protein fused to PK alongside VISTA target protein fused to EA. Upon ligand-induced dimerization of VISTA/VISTA, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Sargramostim Bioassay Kit, 10pl. (93-1078Y3-00112)
The PathHunter Sargramostim Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses GM-CSF or sargramostim-induced dimerization of CSF2RB and CSF2RA receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside CSF2RA target protein fused to EA. Upon ligand-induced dimerization of CSF2RB and CSF2RA, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Meso Scale Discovery R-PLEX Human P-Cadherin ASY
The R-Plex Human P-Cadherin Assay is a multiplex immunoassay kit that enables the simultaneous quantitative measurement of P-Cadherin in human serum plasma and cell culture supernatants It utilizes Meso Scale Discovery electrochemiluminescent detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires an MSD instrument and provides components for one 96-well plate including one standard curve comprised of eight points ranging from 3 2 pg/mL to 10 000 pg/mL P-Cadherin
Abcam Cerivastatin sodium, HMG-CoA reductase inhibitor, 5MG
MW 481.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cerivastatin sodium, HMG-CoA reductase inhibitor, 10MG
MW 481.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cerivastatin sodium, HMG-CoA reductase inhibitor, 25MG
MW 481.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Ral Assay Reagent Ral BP1
Product Source Expressed in E. coli.
Meso Scale Discovery U-PLEX Mouse IL-9 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IL-9 Assay Kit is an electrochemiluminescent immunoassay for the quantitative measurement of mouse interleukin 9 (IL-9) in serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible quantitation of mouse IL-9 with a lower limit of detection of 0 3 pg/mL and an upper limit of 10 000 pg/mL The kit includes a 96-well plate coated with capture antibody detection antibody conjugated to MSD SULFO-TAG calibrators and sample diluent The assay takes approximately 3 5 hours to complete after a 2 hour incubation
Meso Scale Discovery R-PLEX Mouse C1q receptor ASY
The Meso Scale Discovery Mouse C1q Receptor R-PLEX Assay is a multiplex immunoassay that quantitatively measures C1q Receptor in mouse biological samples such as serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay requires an MSD instrument such as SECTOR Imager QuickPlex SQ 120 or QuickPlex SQ 120 The assay has a detection range of 50-100 000 pg/mL and the total assay time is approximately 3 5 hours This assay allows for the rapid reproducible quantification of C1q Receptor from mouse samples
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(3 4 5)P3
Echelon Biosciences - Shuttle PIP Kit - P-9039 - PI(3,4,5)P3 This item is non returnable
Echelon Biosciences Research Labs PI(4)P DiC4 500 ug
Phosphatidylinositol 4-phosphate diC4 (PI(4)P diC4) is a synthetic, purified dibutanoyl PI(4)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex. This item is non returnable
Echelon Biosciences Research Labs PI(3,4,5)P3 DiC16 1 mg
PI(3,4,5)P3 diC16 (Phosphatidylinositol 3,4,5-trisphosphate diC16) is a synthetic, purified dipalmitoyl PI(3,4,5)P3.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. This item is non returnable
Meso Scale Discovery KIT 2400 PHOS-AKT (T308) 5PK
MA2400 Phospho-Akt (Thr308) Whole Cell Lysate Kit (5 Pl)
Genscript Corporation DPPIV/CD26 hFc Chimera Human
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body and a soluble form is present in body fluids There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent